Effects of the Sox17 ∆50 mutation on SOX17 function in mouse embryonic liver development

ABSTRACT: To determine the role of specific cis-regulatory elements within the Sox17 endoderm-preferential TSS2 promoter, we generated Sox17∆50 mutant animals and surveyed how this mutation altered Sox17 expression. Livers were isolated from E12.5 Sox17∆50/∆50 and Sox17+/+ embryos (n = 4 of each genotype), RNA isolated, and bulk RNA-Seq performed.

INSTRUMENT(S): Illumina NovaSeq 6000

ORGANISM(S): Mus musculus

SUBMITTER: Jean-Philippe Cartailler 

PROVIDER: E-MTAB-13982 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress