APMAT analysis reveals associations between antigen-TCR sequences and CD8 T cell phenotype in COVID-19 patients

ABSTRACT: Here, we describe Antigen-TCR Pairing and Multiomic Analysis of T-cells (APMAT), which is an integrated experimental-computational framework designed for the high-throughput capture and analysis of antigen specific CD8 T cells, with paired antigen, TCR sequence, and transcriptome information from the same single cells, from many patient samples in parallel.

INSTRUMENT(S): 10X genomics Chromium X, Illumina NovaSeq 6000, BD FACSAriaII cell sorter

ORGANISM(S): Homo sapiens

SUBMITTER: Jingyi Xie 

PROVIDER: E-MTAB-14002 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress