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The adjuvant effect of MF59 is due to the oil-in-water emulsion formulation, none of the individual components induce a comparable adjuvant effect.

ABSTRACT: Analysis of whole mouse muscle expression signature induced after 6 h by in-vivo intramuscular administration of MF59 or the individual components of MF59 (squalene oil, the surfactants Span 85 and Tween 80, either alone or in combination or the citrate buffer at the same concentrations/dose as within MF59) or PBS as control.

ORGANISM(S): Mus musculus

SUBMITTER: Elaine Tritto

PROVIDER: E-MTAB-1408 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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