Microarray expression profiling of male and female bone marrow derived macrophages from wild type and lysMCre/Irf2bp2flox mice

ABSTRACT: Interferon regulatory factor 2 binding protein 2 (Irf2bp2) is a corepressor of Irf2 that suppresses inflammatory gene expression and promotes the M2 macrophage phenotype in bone marrow derived macrophages (BMDM). Loss of Irf2bp2 in male macrophages promotes an inflammatory phenotype. Here, we compared the expression profile of female BMDM to their male counterparts to identify genes differentially affected by the loss of Irf2bp2 by sex in primary macrophages cultured under basal conditions.

ORGANISM(S): Mus musculus domesticus

SUBMITTER: Alexandre Stewart 

PROVIDER: E-MTAB-14166 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress