Whole Genome Long Read Sequencing of splenocytes from Four Core Genotype (FCG) mice

ABSTRACT: This repository contains whole genome long read sequencing data generated using Oxford Nanopore Technologies from a mouse of the Four Core Genotypes cross. By crossing mice with both a deletion of the sex-determining factor Sry on the Y-chromosome and a transgenic insertion of Sry on Chromosome 3, four combinations of gonadal (testis or ovaries) and chromosomal (XX or XY) are generated, namely XYSry-Chr3Sry+ (gonadal and chromosomal males), XYSry- (gonadal females, chromosomal males), XX (gonadal and chromosomal females), XXChr3Sry+ (gonadal males, chromosomal females). The transgenes were on a C57BL6 genetic background which is crossed with a CAST/EiJ female to allow for the distinction of the parental haplotypes. DNA sequencing was done on a liver sample of the XYSry+ genotype.

INSTRUMENT(S): PromethION

ORGANISM(S): Mus musculus

SUBMITTER:  

PROVIDER: E-MTAB-14291 | biostudies-arrayexpress |

SECONDARY ACCESSION(S): E-MTAB-13585

REPOSITORIES: biostudies-arrayexpress