RNA-seq of ChI-D2RKO mouse nucleus accumbens following a progressive ratio schedule of reinforcement of intravenous cocaine or saline

ABSTRACT: ChI-D2RKO mice showed an altered transcriptomic profile in the dorsomedial striatum in response to contingent cocaine administration. In particular, the expression of critical cocaine-induced transcription factors was not activated in the mutants. This evidence suggests that the altered transcription profile of ChI-D2RKO mice after acute cocaine might lead to long-term changes underlying the reduced PR breakpoint of ChI-D2RKO mice. Thus, RNA-seq was performed on the nucleus accumbens of these mice and their controls.

INSTRUMENT(S): Bioanalyzer, Nanodrop,, Illumina NovaSeq 6000, UC Irvine HPC

ORGANISM(S): Mus musculus

SUBMITTER: Robert Lewis 

PROVIDER: E-MTAB-14303 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress