Single-cell RNA-Seq of IFN-γ stimulated murine bone marrow-derived macrophages (BMDMs) infected Toxoplasma

ABSTRACT: To study the effect of stress on macrophages due to Toxoplasma, we stimulated murine bone marrow-derived macrophages (BMDMs) with IFN-γ (no-stimulate control) and infected them with the apicomplexan parasite Toxoplasma gondii. scRNA-Seq (10X Chromium genomics ) was performed to understand the changes in the immune cells and study the impact of the parasite.

INSTRUMENT(S): Illumina HiSeq 2000

ORGANISM(S): Mus musculus

SUBMITTER: Thomas Otto 

PROVIDER: E-MTAB-14453 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress