MiRNA Expression Profiles in Burkitt and Hodgkin lymphoma cell lines upon Ionizing Radiation Exposure

ABSTRACT: The aim of this study was to identify miRNAs that undergo regulated biogenesis in response to ionizing radiation in B-lymphoma cells. The dataset includes miRNA sequencing data from three Burkitt lymphoma cell lines (ST486, CA46, DG75) and three Hodgkin lymphoma cell lines (L1236, L428, KMH2). Cells were exposed to 4 Gy dose of ionizing radiation and compared to non-irradiated control cells. Single-end RNA sequencing was performed using the Illumina NextSeq500, platform, generating high-quality reads for the analysis of miRNA expression levels and gene expression profiles related to miRNA biogenesis. The raw data analysis followed a multi-step approach. Adapter sequences were removed with Cutadapt-1.11. The reads were then aligned to a modified miRBase (v22.1) using Bowtie-1.2.2, customize

INSTRUMENT(S): NextSeq 500

ORGANISM(S): Homo sapiens

SUBMITTER:  

PROVIDER: E-MTAB-14492 | biostudies-arrayexpress |

SECONDARY ACCESSION(S): E-MTAB-14491

REPOSITORIES: biostudies-arrayexpress