Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

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Age- and ApoE genotype-dependent transcriptomic responses to O3 in the hippocampus of mice


ABSTRACT: We earlier demonstrated that ozone an urban pollutant, accelerates AD-like neuropathology in aging male ApoE3 mice. In this study, we investigate hippocampal transcriptomic alterations in young and aged E3 and E4 mice following O₃ exposure to elucidate the molecular mechanisms underlying O₃-induced AD pathology specifically in old E3 male mice.

INSTRUMENT(S): Illumina NovaSeq X, Illumina® (NEB, USA)

ORGANISM(S): Mus musculus

SUBMITTER: Mary Frances Nakamya 

PROVIDER: E-MTAB-14917 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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