Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

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Trained and untrained human skeletal muscle single-nucleus RNA-sequencing from individuals with type 2 diabetes and control


ABSTRACT: Single-nuclei RNA sequencing (snRNA-seq) data of human muscle cells. The samples are a part of a study investigating the effect of one-legged high-intensity interval training (HIIT) on the nuclear transcriptional response in skeletal muscle. The HIIT was done on one leg on a cycle ergometer, and vastus lateralis muscle biopsies were obtained from both the untrained and trained leg following the two weeks training protocol. The study contains samples from 9 people with Type 2 Diabetes (T2D) and 10 samples from a Body Mass Index (BMI) and age matched control group without diabetes. The experimental study is described in: Dela et al., Acta Physiol, 2019. The snRNA-seq data contains nuclei isolated from 38 available biopsies with the following conditions: Control-Trained, Control-Untrained, Diabetes-Trained, Diabetes-Untrained.

INSTRUMENT(S): NextSeq 550

ORGANISM(S): Homo sapiens

SUBMITTER:  

PROVIDER: E-MTAB-15009 | biostudies-arrayexpress |

SECONDARY ACCESSION(S): ERP171269

REPOSITORIES: biostudies-arrayexpress

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