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Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

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RNA-seq profiling in metachronous colorectal liver metastasis

ABSTRACT: Differential expression analysis was performed on 36 metachronous colorectal liver metastases (mCLM) and adjacent non-malignant liver tissue sample pairs to identify deregulated genes. GSEA and CMS classification were used to explore pathways and stratify tumors. miRNA-mRNA interactions were investigated through co-expression and correlation analysis, with prognostic relevance assessed by survival analysis. This study gave a holistic view of the molecular landscape of mCLM and revealed key deregulated pathways and novel miRNA-mRNA interactions with potential prognostic implications.

INSTRUMENT(S): NextSeq 500

ORGANISM(S): Homo sapiens

SUBMITTER: Viktor Hlavac

PROVIDER: E-MTAB-15022 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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MiRNome profiling in metachronous colorectal liver metastasis

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