SATAY sequencing data from multiple biological replicates of a wild-type strain and a bem1Δbem3Δnrp1Δ mutant strain

ABSTRACT: Functional defects resulting from deleterious mutations can often be restored during evolution by compensatory mutations elsewhere in the genome. Importantly, this process can generate the genetic diversity seen in networks regulating the same biological function in different species. How the options for compensatory evolution depend on the molecular interactions underlying these functions is currently unclear. This dataset, comprising multiple SATAY transposon mutagenesis libraries, was used to examine how gene deletions that compensate for defects in the polarity pathway of Saccharomyces cerevisiae impact the fitness landscape on a genome-wide scale. In total, 12 SATAY libraries were created, consisting of 6 biological replicate experiments of a wild-type strain (yEK19) and 6 biological

ORGANISM(S): Saccharomyces cerevisiae

SUBMITTER: Enzo Kingma 

PROVIDER: E-MTAB-15098 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress