U-87 MG Temozolomide-Induced Senescence RNA-seq Dataset

ABSTRACT: We analyzed the U-87 MG cell line, which was treated with temozolomide for 5 days to induce a senescent state. The study aimed to investigate molecular and phenotypic alterations associated with senescence in the context of a malignant phenotype. Senescence was confirmed through β-galactosidase staining (SA-β-gal), assessment of growth arrest, p21 expression and lipofuscin autofluorescence. Due to inconsistency in paired-end read files, only forward (read1) sequences were retained and submitted as single-end data.

INSTRUMENT(S): Illumina HiSeq 1500

ORGANISM(S): Homo sapiens

SUBMITTER: Alina Isakova 

PROVIDER: E-MTAB-15106 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress