Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

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RNAseq of BMEL cell lines invalidated or not for the expression of the three HP1 isoforms (CBX1, CBX3, CBX5)


ABSTRACT: Expression profiling by high throughput sequencing in Bi-potential Murine Embryonic Liver cells (BMEL cells). Three clones (TKO1, TKO2, TKO3) of BMEL TKO cells invalidated for the expression of the three HP1 isoforms (Cbx1-/-; Cbx3-/-; Cbx5-/-), compared to three clones (Het1, Het32, Het35) of BMEL Het cells (Cbx1+/+; Cbx3+/+; Cbx5+/-) expressing HP1 as controls. Expression profiling was performed on total cell extracts, on cytosolic RNA and on chromatin-enriched RNA.

INSTRUMENT(S): Illumina NovaSeq 6000

ORGANISM(S): Mus musculus

SUBMITTER: Christophe RACHEZ 

PROVIDER: E-MTAB-15194 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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