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Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

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Single-cell RNA-seq analysis of embryonic AGM+VU from Runx1 enhancer-reporter transgenic mice

ABSTRACT: During embryonic development, haematopoietic stem and progenitor cells originate from haemogenic endothelium (HE) via an endothelial-to-haematopoietic transition (EHT), which is dependent on the transcription factor Runx1. Here, we transcriptionally profiled embryonic cells isolated from two Runx1 enhancer-reporter transgenic mouse models (23GFP tg and 110GFP tg mice) that mark distinct subsets of Runx1-expressing cells in the developing embryo.

INSTRUMENT(S): Illumina NovaSeq 6000

ORGANISM(S): Mus musculus

SUBMITTER: Giorgio Anselmi

PROVIDER: E-MTAB-15202 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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