Expression profiling of murine E10.5 TLR2+ CD11b+ embryonic phagocytes by comparative microarray analyses

ABSTRACT: The detection of Toll-like receptor 2 (TLR2) expression on E10.5 early embryonic phagocytes prompted us to determine the list of markers co-expressed with TLR2 in a cell-type specific manner. Thus, a comparative expression profiling of cDNAs between murine E10.5 TLR2+ CD11b+ embryonic cells and TLR2+ CD11b+ peritoneal macrophages as well as between TLR2+ CD11b+ and TLR2- CD11b- embryonic cells were performed using Illumina arrays. Each pairwise comparison experiment was performed in triplicate. Our data identified several novel markers of early embryonic phagocytes that could be utilized for the isolation, manipulation and functional characterization of this poorly characterized cell population. In this context, Ferroportin1 (Slc40a1) was highly expressed on E10.5 phagocytes what suggests

ORGANISM(S): Mus musculus

SUBMITTER: Michal Kolar 

PROVIDER: E-MTAB-1537 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress