Methylation profiling of DMGO
Ontology highlight
ABSTRACT: Diffuse midline glioma (DMG) is a lethal pediatric brain cancer with limited treatment options. We developed a human brainstem organoid model to study H3.3K27M-driven DMG, enabling formation of patient-like tumors with molecular heterogeneity. To characterize the resulting tumor we performed DNA methylation and compared the generated tumor with methylation data from DMG, pGBM and PFA ependymoma patients.
INSTRUMENT(S): Sony SH8000S Cell Sorter, Illumina iScan
ORGANISM(S): Homo sapiens
SUBMITTER: Hendrikus Ariese
PROVIDER: E-MTAB-15559 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
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