Unknown,Transcriptomics,Genomics,Proteomics

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Methylation profiling of DMGO


ABSTRACT: Diffuse midline glioma (DMG) is a lethal pediatric brain cancer with limited treatment options. We developed a human brainstem organoid model to study H3.3K27M-driven DMG, enabling formation of patient-like tumors with molecular heterogeneity. To characterize the resulting tumor we performed DNA methylation and compared the generated tumor with methylation data from DMG, pGBM and PFA ependymoma patients.

INSTRUMENT(S): Sony SH8000S Cell Sorter, Illumina iScan

ORGANISM(S): Homo sapiens

SUBMITTER: Hendrikus Ariese 

PROVIDER: E-MTAB-15559 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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