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RNA-seq profiling of six fetal tissues at day 63 of gestation from a reciprocal backcross of German Landrace and Piétrain

ABSTRACT: Utilizing a reciprocal backcross design: F₁ (German Landrace × Pietrain) sows × GL or Pi sires (Ponsuksili et.al. 2025; doi:https://doi.org/10.1098/rsob.240285), we profiled six fetal tissues (liver, brain, muscle, kidney, ovary, and testis) at day 63 of gestation. Our study aimed to: (i) characterize transcriptomic differences both between backcross groups (F₁×GL and F₁×Pi) across tissue types; (ii) map tissue-specific ASE landscapes within each backcross group; and (iii) identification of differential ASE (dASE) genes by comparing allele-specific expression between reciprocal backcrosses within each tissue. All together, we provide insights into paternal genetics potentials of fetal programming for animal breeding.

INSTRUMENT(S): NextSeq 2000

ORGANISM(S): Sus scrofa

SUBMITTER: Nares Trakooljul

PROVIDER: E-MTAB-15588 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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