Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

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ScRNA-seq of posterior brain organoid morphogen screen


ABSTRACT: To pattern novel posterior brain regions, we used a multiplexed morphogen screen with a single-cell sequencing readout to test 48 concentrations and combinations of 10 morphogens involved in brain patterning. This screen revealed the emergence of regions harboring under-represented cell types, such as medulla glycinergic neurons and cerebellum glutamatergic cells, that expanded mesencephalon and rhombencephalon models.

INSTRUMENT(S): Illumina NovaSeq 6000

ORGANISM(S): Homo sapiens

SUBMITTER: Nadezhda Azbukina 

PROVIDER: E-MTAB-15660 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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