Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

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One way or another: Differential impact of pharmacologic inhibitors on extracellular vesicles derived from resting neutrophils


ABSTRACT: We performed a systematic investigation of seven pharmacologic inhibitors (calpeptin, D-pantethine, Y27632, cytochalasin D, GW4869, R5421, and Nexinhib20) on quantitative and qualitative EV properties derived from resting neutrophils. We measured EV numbers, size distribution, total lipid, protein, and RNA content. We also analyzed the EV morphology by cryo-EM and EV cargo qualitatively by mass spectrometry and RNA sequencing (mRNA, miRNA).

INSTRUMENT(S): DNBSEQ-G50

ORGANISM(S): Homo sapiens

SUBMITTER: Viktoria Szeifert 

PROVIDER: E-MTAB-15978 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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