Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

0

Oslo_BMM


ABSTRACT: Investigation of miRNA expression in colorectal cancer tumors using massive parallel sequencing

INSTRUMENT(S): Illumina Genome Analyzer IIx

ORGANISM(S): Homo sapiens

SUBMITTER: Kjersti Flatmark 

PROVIDER: E-MTAB-1649 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications


Colorectal cancer (CRC) is one of the leading causes of cancer related deaths and the search for prognostic biomarkers that might improve treatment decisions is warranted. MicroRNAs (miRNAs) are short non-coding RNA molecules involved in regulating gene expression and have been proposed as possible biomarkers in CRC. In order to characterize the miRNA transcriptome, a large cohort including 88 CRC tumors with long-term follow-up was deep sequenced. 523 mature miRNAs were expressed in our cohort,  ...[more]

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