RNA-seq analysis of cardiac fibrosis in mouse hearts 28 days post-myocardial infarction with (MIEru) or without (CONMI) dietary erucic acid supplementation
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ABSTRACT: This dataset contains RNA sequencing data from mouse cardiac tissue collected 28 days after myocardial infarction (MI). The study investigates the effect of dietary erucic acid supplementation on post-MI cardiac fibrosis. All animals underwent MI surgery. The experimental group (MIEru, n=4) received a diet containing 20% erucic acid for the entire 28-day post-operative period. The control group (CON, n=4) received a standard diet without erucic acid supplementation following MI. RNA was extracted from whole heart tissue (with a focus on the fibrotic region/infarct border zone) and subjected to standard Illumina library preparation and paired-end sequencing. The data can be used to explore the transcriptional profile associated with post-MI remodeling and the impact of erucic acid on pathways related to fibrosis, inflammation, and metabolism.
INSTRUMENT(S): Illumina NovaSeq 6000
ORGANISM(S): Mus musculus
SUBMITTER: Leng jiajie
PROVIDER: E-MTAB-16586 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
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