Global epigenomic profiling of corticotroph pituitary neuroendocrine tumors

ABSTRACT: Corticotroph pituitary neuroendocrine tumors (PitNETs) are heterogeneous sellar neoplasms with variable clinical manifestations and growth behaviour. In this study, epigenomic data was generated as part of an integrative meta-analysis of corticotroph PitNETs, which included epigenomic, transcriptomic, and proteomic investigations. This deposit comprises idat files of tumor samples and adenohypophysial non-neoplastic control samples. These data were integrated with previously published external molecular datasets. The combined analyses defined four clinically relevant molecular subgroups of corticotroph PitNETs.

ORGANISM(S): Homo sapiens

SUBMITTER: Matthias Dottermusch 

PROVIDER: E-MTAB-16589 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress