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Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

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SIRV2infection

ABSTRACT: Archaeal viruses display unusually high genetic and morphologic diversity. The Sulfolobus islandicus Rod Shaped Virus 2 (SIRV2) is a model to study virus-host interactions in Archaea. It is a lytic virus that exploits a unique egress mechanism based on formation of remarkable pyramidal structures on the host cell envelope. The hyperthermophilic Sulfolobus islandicus LAL14/1 is the natural host for SIRV2. RNA was isolated at 0,1,2,3,5,7 and 9 hours after SIRV2 infection of two S.islandicus cultures and analysed with whole transcriptome sequencing (RNAseq). As a control RNA was isolated at the same time points from two uninfected cultures.

INSTRUMENT(S): Illumina HiSeq 2000

ORGANISM(S): Sulfolobus islandicus LAL14/1

SUBMITTER: Bernd Jagla

PROVIDER: E-MTAB-1660 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Massive activation of archaeal defense genes during viral infection.

Quax Tessa E F TE Voet Marleen M Sismeiro Odile O Dillies Marie-Agnes MA Jagla Bernd B Coppée Jean-Yves JY Sezonov Guennadi G Forterre Patrick P van der Oost John J Lavigne Rob R Prangishvili David D

Journal of virology 20130522 15

Archaeal viruses display unusually high genetic and morphological diversity. Studies of these viruses proved to be instrumental for the expansion of knowledge on viral diversity and evolution. The Sulfolobus islandicus rod-shaped virus 2 (SIRV2) is a model to study virus-host interactions in Archaea. It is a lytic virus that exploits a unique egress mechanism based on the formation of remarkable pyramidal structures on the host cell envelope. Using whole-transcriptome sequencing, we present here ...[more]

PMID: 23698312

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