Human adipose tissue single-nucleus RNA-sequencing before and after lifestyle intervention

ABSTRACT: Single-nuclei RNA sequencing (snRNA-seq) data of human adipose tissue. The samples are a part of a study investigating the effect of Lifestyle intervention on human adipose tissue. The 10 participants represented in this study were severely obese at project start with a mean BMI of 46.0 ± 3.1 kg/m2 and a BMI range of 31.4–63.0 kg/m2, with a 50/50 female/male ratio. After intervention mean BMI was 40.8 ± 2.8 kg/m2 with BMI range: 27.4–57.5 kg/m2. These participants took part in 15-weeks of consecutive lifestyle intervention consisting of a hypocaloric diet and moderate physical activity. Hypocaloric diet was calculated for the specific participant and calculated to reduce the subject’s body weight by approximately 1% per week. The exercise consisted of 2-3 hours of moderate-intensity physic

INSTRUMENT(S): 10X Chromium Controller, Illumina NovaSeq 6000

ORGANISM(S): Homo sapiens

SUBMITTER: Thomas Åskov Pedersen 

PROVIDER: E-MTAB-16620 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress