Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

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Profiling of H3.3


ABSTRACT: Histone variants can effect nucleosome stability or affect histone of DNA modifications. H3.3 is a major H3 histone variant that is incorporated into chromatin outside of S-phase in various eukaryotes. In animals, H3.3 is associated with active transcription and possibly maintenance of transcriptional memory. Plant H3.3, which evolved independently of animal H3.3, is much less well understood. We performed ChIP-chip using chromatin from rosette leaves of 35S:H3.3-YFP plants.

ORGANISM(S): Arabidopsis thaliana

SUBMITTER: Lars Hennig 

PROVIDER: E-MTAB-1685 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

Arabidopsis replacement histone variant H3.3 occupies promoters of regulated genes.

Shu Huan H   Nakamura Miyuki M   Siretskiy Alexey A   Borghi Lorenzo L   Moraes Izabel I   Wildhaber Thomas T   Gruissem Wilhelm W   Hennig Lars L  

Genome biology 20140321 4


<h4>Background</h4>Histone variants establish structural and functional diversity of chromatin by affecting nucleosome stability and histone-protein interactions. H3.3 is an H3 histone variant that is incorporated into chromatin outside of S-phase in various eukaryotes. In animals, H3.3 is associated with active transcription and possibly maintenance of transcriptional memory. Plant H3 variants, which evolved independently of their animal counterparts, are much less well understood.<h4>Results</  ...[more]

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