Trancription profiling by array of human pulmonary and circulating CD8 cells in COPD

ABSTRACT: Background: CD8 cells seem to play an important role in the pathogenesis of chronic obstructive pulmonary disease (COPD). However, relatively little is known about their phenotype and function. Aims: To define the transcriptome of pulmonary CD8 cells in COPD and compare to paired circulating CD8 cells and smoker control pulmonary CD8 cells. COPD was defined according to the Global initiative for chronic Obstructive Lung Disease guidelines. Severity of disease was defined according to the patients lung function. In particular the forced evpiratroy volume in 1 second (FEV1).

ORGANISM(S): Homo sapiens

SUBMITTER: Seamus Grundy 

PROVIDER: E-MTAB-1688 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress