Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

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Tissue-Specific Transcriptomic Insights into Myxozoan Infections: Immune and Stress Responses in the Kidney and Head Cartilage of Rainbow Trout


ABSTRACT: This experiment investigates how sequential infections with Myxobolus cerebralis and Tetracapsuloides bryosalmonae alter immune responses in rainbow trout. Using RNA-seq of kidney and head cartilage tissues, the study compares transcriptomic changes during single infections and sequential co-infection to determine how combined parasite exposure reshapes host immune pathways and tissue responses.

INSTRUMENT(S): Illumina NovaSeq 6000

ORGANISM(S): Oncorhynchus mykiss

SUBMITTER: Naveed Akram 

PROVIDER: E-MTAB-16908 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

Transcriptomic Analysis of the Rainbow Trout Response to Single and Co-Infections with <i>Myxobolus cerebralis</i> and <i>Tetracapsuloides bryosalmonae</i> at Sites of Parasite Entry.

Akram Naveed N   Ertl Reinhard R   Ghanei-Motlagh Reza R   Secombes Christopher J CJ   El-Matbouli Mansour M   Holzer Astrid S AS   Saleh Mona M  

International journal of molecular sciences 20250822 17


Parasitic infections, such as those caused by the myxozoans <i>Myxobolus cerebralis</i> and <i>Tetracapsuloides bryosalmonae</i>, pose major threats to wild and farmed salmonids due to severe tissue damage and impairment of the host immune system. While individual infections have been studied, limited information is available on the host response during co-infection. This study investigated the transcriptomic immune response of rainbow trout (<i>Oncorhynchus mykiss</i>) during single and sequent  ...[more]

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