ScRNA-seq of organoids injected subcutaneously into C57BL/6 mice. Mice were treated with CD4 depletion antibody, CD8 depletion antibody or IgG control

ABSTRACT: Genetically engineered organoids with the genetic background VBPNA were injected subcutaneously into immunocompetent mice. The mice were treated with CD4 T cells depletion antibody, CD8 T cell depletion antibody or IgG control. The tumors sizes were measured weekly. The intent of the experiment was to determine if the distinct T cell population have an effect on tumor growth, cancer cell state and immune cells.

INSTRUMENT(S): Illumina NovaSeq 6000

ORGANISM(S): Mus musculus

SUBMITTER: Manuel Mastel 

PROVIDER: E-MTAB-17106 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress