Single cell RNA seq of human CD3+ splenocytes from humanized mice

ABSTRACT: Comparing human T cell repertoire development in humanized mice using CD34+ cell transplantation in NSG strain versus NSG without murine MHC (DKO). Additionally, comparing two preconditioning protocols: busulfan (BU) versus irradiation (IR). In total 4 groups compared: DKO-BU, DKO-IR, NSG-BU and NSG-IR. 3 CB donors were used to humanize these mice.

INSTRUMENT(S): Illumina NovaSeq X

ORGANISM(S): Mus musculus

SUBMITTER: Milita Darguzyte 

PROVIDER: E-MTAB-17275 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress