Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

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Pancreatic islet epigenomics reveals enhancer clusters that are enriched in Type 2 diabetes risk variants


ABSTRACT: We combined ChIP-seq of chromatin marks and key islet transcription factor with RNA-seq in human islets to map cis-regulatory networks in this primary tissue. The output of this project provides a reference map to dissect genetic variants that alter the susceptibility for Type 2 diabetes, and assist efforts to generate new beta-cells by transcriptional programming strategies

INSTRUMENT(S): Illumina Genome Analyzer IIx, Illumina HiSeq 2000

ORGANISM(S): Homo sapiens

SUBMITTER: Lorenzo Pasquali 

PROVIDER: E-MTAB-1919 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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