STOX1 placenta w/o aspirin

ABSTRACT: STOX1 overexpressing placentas generate preeclampsia-like symptoms in pregnant mice. These symptoms are reverted by aspirin. The experiment aims at analyzing placental expression in Transgenic/non transgenic with and withou aspirin, in the placentas at 16,5 days post-coïtum. There are two strains of transgenic mice that express the transgene at different levels: STOX42 about 15 fold that of STOX13. STOX13 expressed the human STOX1 roughly at the level of the mouse endogeneous Stox1 in the placenta.

ORGANISM(S): Mus musculus

SUBMITTER: Daniel Vaiman 

PROVIDER: E-MTAB-1970 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress