Tri-KIX_DP_thymocytes

ABSTRACT: To determine the effect of mutation of the KIX domain of CBP and p300 on gene expression, thymuses dissected from four to seven week old wild type and CBP KIX/KIX;p300 +/KIX adult mice were dissociated into single cell suspesions, antibody stained for CD4 and CD8, sorted for CD4+ CD8+ double positive thymocytes, RNA was made from the sorted cells and transcriptional profiling by array was carried out. CD4+CD8+ double positive thymocytes were chosen because these cells express c-Myb.

ORGANISM(S): Mus musculus

SUBMITTER: Lawryn Kasper 

PROVIDER: E-MTAB-1974 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress