Unknown,Transcriptomics,Genomics,Proteomics

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Molecular characterisation of adipose tissue in the African elephant (Loxodonta africana)

ABSTRACT: The African elephant (Loxodonta africana) is experiencing serious challenges to optimal reproduction in captivity. The physiological and molecular basis of this impaired fertility remains unknown. A functional link between nutritional status, body condition score and fertility is well established in humans and many other species, where adipose tissue production of the hormone leptin has emerged as a crucial reproductive regulator. This report forms the basis for future studies to address the effect of nutrient composition and body condition on captive and wild elephants.

ORGANISM(S): Loxodonta africana

SUBMITTER: Tom Giles 

PROVIDER: E-MTAB-2024 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Adipose tissue (AT) is a dynamic and flexible organ with regulatory roles in physiological functions including metabolism, reproduction and inflammation; secreted adipokines, including leptin, and fatty acids facilitate many of these roles. The African elephant (Loxodonta africana) is experiencing serious challenges to optimal reproduction in captivity. The physiological and molecular basis of this impaired fertility remains unknown. AT production of leptin is a crucial molecular link between nu  ...[more]