Multi-layer omics dataset for cross-species translational systems biology

ABSTRACT: Inferring in humans biological responses to external cues such as drugs, chemicals, viruses and hormones, is an essential question in biomedicine and cannot be easily studied in humans. Thus, biomedical research has continuously relied on animal models for studying the impact of these compounds and attempted to M-^StranslateM-^T the results to humans. In this context, the Systems Biology Verification for Industrial Methodology for Process Verification in Research (SBV IMPROVER) initiative had run a Species Translation Challenge for the scientific community to explore and understand the limit of translatability from rodent to human using systems biology. Therefore, a multi-layer omics dataset was generated that comprised of phosphoproteomics, transcriptomics and cytokine data derived from n

INSTRUMENT(S): Affymetrix GeneChip Scanner 3000 7G

ORGANISM(S): Rattus norvegicus

SUBMITTER: Sam Ansari 

PROVIDER: E-MTAB-2091 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress