Responses of cardiac tissue of the crucian carp (Carassius carassius) to anoxia stress
Ontology highlight
ABSTRACT:
ORGANISM(S): Carassius carassius
SUBMITTER: Andrew R. Cossins
PROVIDER: E-MTAB-2516 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
Life without oxygen: gene regulatory responses of the crucian carp (Carassius carassius) heart subjected to chronic anoxia.
Stensløkken Kåre-Olav KO Ellefsen Stian S Vasieva Olga O Fang Yongxiang Y Farrell Anthony P AP Olohan Lisa L Vaage Jarle J Nilsson Göran E GE Cossins Andrew R AR
PloS one 20141105 11
Crucian carp are unusual among vertebrates in surviving extended periods in the complete absence of molecular oxygen. During this time cardiac output is maintained though these mechanisms are not well understood. Using a high-density cDNA microarray, we have defined the genome-wide gene expression responses of cardiac tissue after exposing the fish at two temperatures (8 and 13 °C) to one and seven days of anoxia, followed by seven days after restoration to normoxia. At 8 °C, using a false disco ...[more]
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