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Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

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MoMaTEC1403

ABSTRACT: Aim for investigation of expression patterns of endometrial cancers

ORGANISM(S): Homo sapiens

SUBMITTER: Ingvild Tangen1,2*

PROVIDER: E-MTAB-2532 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Switch in FOXA1 status associates with endometrial cancer progression.

Tangen Ingvild Løberg IL Krakstad Camilla C Halle Mari K MK Werner Henrica M J HM Oyan Anne M AM Kusonmano Kanthida K Petersen Kjell K Kalland Karl Henning KH Akslen Lars A LA Trovik Jone J Hurtado Antoni A Salvesen Helga B HB

PloS one 20140521 5

<h4>Background</h4>The transcription factor Forkhead box A1 (FOXA1) is suggested to be important in hormone dependent cancers, although with little data for endometrial cancer. We investigated expression levels of FOXA1 in primary and metastatic endometrial cancer in relation to clinical phenotype, and transcriptional alterations related to FOXA1 status.<h4>Methods</h4>Protein expression of FOXA1 was explored by immunohistochemistry in 529 primary and 199 metastatic endometrial carcinoma lesions ...[more]

PMID: 24849812

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