The transcriptome of TRPV1-positive sensory neurons revealed by subgroup-elimination transcriptomics

ABSTRACT: We developed an approach to rapidly eliminate the subgroup of sensory neurons expressing the heat-gated cation channel TRPV1 from dissociated rat sensory ganglia using agonist treatment followed by density centrifugation. To identify transcripts predominantly expressed in TRPV1-positive neurons, we compared the transcriptome of all cells within sensory ganglia versus all cells without TRPV1 expressing neurons using RNA-Seq.

INSTRUMENT(S): AB 5500xl Genetic Analyzer

ORGANISM(S): Rattus norvegicus

SUBMITTER: Robert Weissmann 

PROVIDER: E-MTAB-2789 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress