20-hydroxyecdysone (20E) induced transcriptional changes in the atrium and spermatheca of female Anopheles gambiae mosquitoes 24 hours after 20E injection compared to ethanol treated controls.

ABSTRACT: Male Anophele gambiae mosquitoes transfer the steroid hormone 20-hydroxyecdysone (20E) to the female lower reproductive tract during mating. We have shown that this sexually transferred hormone is a key regulator of monandry and oviposition in An. gambiae females. In order to identify possible molecular pathways underlying the effects induced by sexually transferred 20E we investigated the transcriptional response in the atrium and spermatheca at 24 hours after 20E injection in the thorax of virgin females, which delivers to these reproductive tissues 20E levels comparable to those detected after mating. By comparing these results to those of microarrays assessing the post-mating transcriptional response in the female lower reproductive tract (LRT) at 24 hours post copulation, we were able

ORGANISM(S): Anopheles gambiae

SUBMITTER: Sara Mitchell 

PROVIDER: E-MTAB-3023 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress