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Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

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Differential Gene Expression Profile in the Rat Caudal Vestibular Nucleus is Associated with Individual Differences in Motion Sickness Susceptibility

ABSTRACT: Motion sickness susceptible (MSS) and insusceptible (inMSS) rats were identified by quantifying rotation-induced MS symptoms: defecation and spontaneous locomotion activity. Microarray analysis was used to screen differentially expressed genes in the caudal vestibular nucleus (CVN) after rotation.

ORGANISM(S): Rattus norvegicus

SUBMITTER: Yi-ling Cai

PROVIDER: E-MTAB-3213 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Differential Gene Expression Profile in the Rat Caudal Vestibular Nucleus is Associated with Individual Differences in Motion Sickness Susceptibility.

Wang Jun-Qin JQ Qi Rui-Rui RR Zhou Wei W Tang Yi-Fan YF Pan Lei-Lei LL Cai Yi-Ling YL

PloS one 20150424 4

<h4>Objective</h4>To identify differentially expressed genes associated with motion sickness (MS) susceptibility in the rat caudal vestibular nucleus.<h4>Methods</h4>We identified MS susceptible (MSS) and insusceptible (inMSS) rats by quantifying rotation-induced MS symptoms: defecation and spontaneous locomotion activity. Microarray analysis was used to screen differentially expressed genes in the caudal vestibular nucleus (CVN) after rotation. Plasma stress hormones were identified by radioimm ...[more]

PMID: 25910039

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