Transcription profiling of Mitotane induced expression changes in adrenocortical carcinoma cell-line NCI-H295

ABSTRACT: Human ACC cell-line NCI-H295 was treated in biological triplicate for 6 hours with 50M-eM-5M (16 mg/l) and 100M-eM-5M (32 mg/l) mitotane or diluent as control.Genome-wide gene expression analyses were performed using the Affymetrix HG_133_plus2 array to identify the molecular mechanisms underlying mitotane action in an unsupervised fashion.

INSTRUMENT(S): in a humid atmosphere at 37M-eM-!C and 5% CO2

ORGANISM(S): Homo sapiens

SUBMITTER: Silviu Sbiera 

PROVIDER: E-MTAB-3241 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress