Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

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MicroRNA profiling by array of NCI-60 human cancer cell-lines


ABSTRACT: Affymetrix GeneChip miRNA arrays were used to profile the expression of microRNAs in cells of sixty NCI-60 cancer cell-lines

ORGANISM(S): Homo sapiens

DISEASE(S): gliosarcoma

SUBMITTER: Santosh Patnaik 

PROVIDER: E-MTAB-327 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

Expression of microRNAs in the NCI-60 cancer cell-lines.

Patnaik Santosh K SK   Dahlgaard Jesper J   Mazin Wiktor W   Kannisto Eric E   Jensen Thomas T   Knudsen Steen S   Yendamuri Sai S  

PloS one 20121128 11


The NCI-60 panel of 60 human cancer cell-lines of nine different tissues of origin has been extensively characterized in biological, molecular and pharmacological studies. Analyses of data from such studies have provided valuable information for understanding cellular processes and developing strategies for the diagnosis and treatment of cancer. Here, Affymetrix® GeneChip™ miRNA version 1 oligonucleotide microarrays were used to quantify 847 microRNAs to generate an expression dataset of 495 (58  ...[more]

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