Single-cell transcriptome sequencing from mouse mTECs

ABSTRACT: Promiscuous gene expression (pGE) of tissue-restricted antigens in medullary thyme ephitelial cells (mTECs) is essential for self-tolerance induction and to prevent autoimmunity. We sequenced single mTEC transcriptomes to explore gene expression heterogeneity and to discover patterns of regulation of pGE.

INSTRUMENT(S): Illumina HiSeq 2500, Illumina MiSeq

ORGANISM(S): Mus musculus

SUBMITTER: Alejandro Reyes 

PROVIDER: E-MTAB-3346 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress