Dose response of the BET inhibitor JQ1 in Small-Cell Lung Cancer cell lines.

ABSTRACT: This is a Dose response experiment carried out using the BET inhibitor JQ1 in SCLC cell lines. Approximately 1x106 cells of cell lines, DMS-53, H69, H1694, H1048, H2227 were treated for 2 hours with a 12 point dose range of JQ1 (7500nM to 0.04nM). Lysates were collected at the end of the treatment in 300ul TRI reagent for RNA preparation for expression profiling.

INSTRUMENT(S): Gene Titan

ORGANISM(S): Homo sapiens

SUBMITTER: Petra Ross-Macdonald 

PROVIDER: E-MTAB-3449 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress