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Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

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Methylation profiling of NimbleGen Mouse DNA Methylation 3x720K CpG Island Plus RefSeq Promoter Array

ABSTRACT: NimbleGen Mouse DNA Methylation 3x720K CpG Islands Pus RefSeq Promoter Array was used to perform a DNA methylome analysis to unravel the molecular mechanism underlying the dedifferentiation and cell cycle reentry of mouse adult cardiomyocytes (ACMs). A total of six DNA samples (10 ng each) derived from the population cells from either control adult cardiomyocytes or mCPCs were subject to whole genome amplification and then 2.5 Âµg of amplified products were used for DNA methylome analysis. There were three biological replicates in each group (both ACM controls and mCPCs). The whole genome methylome data using NimbleGen Mouse 2.1M array and genomic DNA derived from population cells for both control adult cardiomyocytes and mCPC can be found in E-MTAB-3984. Single-cell whole-transcriptome microarray data using Affymetrix Mouse Genome 430 2.0 Array can be found in E-MTAB-3981.

ORGANISM(S): Mus musculus

SUBMITTER: Xin Chen

PROVIDER: E-MTAB-3982 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Methylation profiling of NimbleGen Mouse 2.1M Array

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