RNA Affymetrix microarray analysis of colonic mucosal layer of Apc Min/+ mice fed or not with maslinic acid.

ABSTRACT: This experiment reports the RNA microarray data from the microarray analysis performed to the RNA isolated from colonic mucosal layer of Apc Min/+ mice. Apc Min/+ mice develop polyps in both the small and large intestine, with a greater incidence of intestinal adenomas observed in the former. We wanted to evaluate if maslinic acid (MA), a natural pentacyclic triterpene widely present in dietary plants and in olive fruit skins, could prevent spontaneous intestinal tumorigenesis in Apc Min/+ mice and through with mechanism MA executes its function. To do so, Apc Min/+ mice were fed for 6 weeks with a standard diet (control animals) or with the same diet supplemented with 100 mg of MA/kg feed (MA-treated animals). After 6 weeks, animals were killed and large intestine of each dead mouse was r

ORGANISM(S): Mus musculus

SUBMITTER: Silvia Marin 

PROVIDER: E-MTAB-4007 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress