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Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

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RNA-Sequencing of wild type and UCP1-null beige adipose tissue

ABSTRACT: Since brown adipose tissue (BAT) dissipates energy through UCP1, BAT has garnered attention as a therapeutic intervention for obesity and metabolic diseases including type 2 diabetes. As we better understand the roles of classical brown and beige adipocytes, increased beige fat mass in response to a variety of external/internal cues is associated with significant improvements in glucose and lipid homeostasis that may not be entirely mediated by UCP1. We aim to analyze transcriptome of wild type and UCP1-null beige adipocyte to identify the UCP1-independent function.

INSTRUMENT(S): NextSeq 500

ORGANISM(S): Mus musculus

SUBMITTER: Kosaku Shinoda

PROVIDER: E-MTAB-4085 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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