DNA methylation patterns in perpheral blood samples from pre- and post-pubertal boys and girls

ABSTRACT: The COPENHAGEN Puberty Study is a combined cross sectional and longitudinal population based cohort study of healthy Danish children and adolescents. The clinical evaluations were performed by trained physicians and included pubertal staging of breast development according to Tanner´s classification evaluated by palpation. As a measure of pubertal onset a testicular volume of 4 ml or a breast tanner stage of B2 or more was used for boys and girls, respectively. The mean age between two examinations where this threshold was reached was used as their age of pubertal onset. Pre- and post-pubertal samples from 20 girls and 31 boys, in total 102 samples, were normalised using a Subset quantile Within-Array Normalization (SWAN) procedure and probes containing SNPs in the CpG or extension sites

INSTRUMENT(S): x86_64-apple-darwin13.4.0 (64-bit)

ORGANISM(S): Homo sapiens

SUBMITTER: Kristian Almstrup 

PROVIDER: E-MTAB-4187 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress