Genomic alterations underlie a pan-cancer metabolic transcriptome shift associated with hypoxic selection

ABSTRACT: Hypoxia is a known driver of genomic instability in solid tumours. Here we perform in-vivo profiling of early genomic changes induced by hypoxia in colorectal cancer cell (HCT116) xenografts using Bevacizumab; an anti-angiogenic drug inducing hypoxia.

ORGANISM(S): Homo sapiens

SUBMITTER: Syed Haider 

PROVIDER: E-MTAB-4200 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress