Widespread Dynamic DNA Methylation in Response to Biotic Stress

ABSTRACT: Regulation of gene expression by DNA methylation is crucial for defining cellular identities and coordinating organism-wide developmental programs in many organisms. In plants, modulation of DNA methylation in response to environmental conditions represents a potentially robust mechanism to regulate gene expression networks, however, examples of dynamic DNA methylation are largely limited to gene imprinting. We discovered an unexpected role for DNA methylation in regulation of the Arabidopsis thaliana immune system. Profiling the DNA methylomes of plants exposed to bacterial pathogen, avirulent bacteria, or salicylic acid (SA) hormone revealed numerous stress-induced differentially methylated regions (DMRs), many of which were intimately associated with differentially expressed genes. In r

INSTRUMENT(S): Illumina Genome Analyzer II

ORGANISM(S): Arabidopsis thaliana

SUBMITTER: Joseph Ecker 

PROVIDER: E-MTAB-4226 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress